Improving the congruity of preclinical models with cancer as it is manifested in humans is a potential way to mitigate the high attrition rate of new cancer therapies in the clinic.In this regard, three-dimensional (3D) tumor cultures in vitro have recently regained interest as they have been acclaimed to have higher similarity to tumors in vivo th
Acute effects of caffeine and paracetamol on velocity and power in resistance exercise
This study aimed to explore the isolated and combined effects of caffeine and paracetamol (acetaminophen) on velocity and power in resistance exercise.Twenty-eight resistance-trained men and women participated Shirts Women’s Gray Howdy Wood Crop Top in this randomized, double-blind, placebo-controlled, crossover study.The participants performed t
Reconfigurable 3D CAD Feature Recognition Supporting Confluent n-Dimensional Topologies and Geometric Filters for Prismatic and Curved Models
Feature Recognition (FR) in Computer-aided Design (CAD) models is central for Design and Manufacturing.FR is a problem whose computational burden is intractable (NP-hard), given that its underlying task is the detection of graph isomorphism.Until now, compromises have been reached by only using FACE-based geometric information of prismatic CAD mode
Successful Aging in Individuals From Less Advantaged, Marginalized, and Stigmatized Backgrounds
[Background] Health and well-being in later life are heavily influenced by behaviors across the life course, which in turn are influenced by a variety of wider contextual, social, economic, and organizational factors.There is considerable potential for inequalities in health-promoting behaviors and health outcomes, arising from poverty, social, and
QTLs underlying the genetic interrelationship between efficient compatibility of Bradyrhizobium strains with soybean and genistein secretion by soybean roots.
Soybean plants establish symbiotic relationships with soil rhizobia which form nodules on the plant roots.Nodule formation starts when the plant roots exudate isoflavonoids that induce nod gene expression of a specific Bradyrhizobium.We examined the specific indigenous rhizobia that form nodules with the soybean cultivars Peking and Tamahomare in d